Brigitte Meunier Selected Research

Atovaquone (Mepron)

1/2021	Revisiting the mode of action of the antimalarial proguanil using the yeast model.
10/2005	Re-examination of inhibitor resistance conferred by Qo-site mutations in cytochrome b using yeast as a model system.
4/2005	Cytochrome b mutations that modify the ubiquinol-binding pocket of the cytochrome bc1 complex and confer anti-malarial drug resistance in Saccharomyces cerevisiae.
1/2004	Molecular basis for atovaquone resistance in Pneumocystis jirovecii modeled in the cytochrome bc(1) complex of Saccharomyces cerevisiae.
8/2003	Molecular basis for atovaquone binding to the cytochrome bc1 complex.

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Brigitte Meunier Research Topics

Disease

7	Malaria 01/2021 - 01/2004
3	Neoplasms (Cancer) 01/2020 - 07/2016
3	Mitochondrial Diseases (Mitochondrial Disease) 12/2013 - 04/2009
2	Glioblastoma (Glioblastoma Multiforme) 07/2019 - 07/2015
2	Toxoplasmosis 09/2012 - 08/2003
2	Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia) 01/2004 - 08/2003
2	Falciparum Malaria (Plasmodium falciparum Malaria) 01/2004 - 08/2003
1	Hypoxia (Hypoxemia) 01/2020
1	Brain Diseases (Brain Disorder) 01/2020
1	Cataract (Cataracts) 01/2020
1	Galactosemias (Galactosemia) 01/2020
1	Starvation 11/2019
1	Cytochrome-c Oxidase Deficiency 12/2013
1	Seizures (Absence Seizure) 05/2009
1	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 05/2009
1	Lactic Acidosis 05/2009
1	Coenzyme Q10 Deficiency 05/2009
1	Cardiomyopathies (Cardiomyopathy) 04/2004
1	Pneumonia (Pneumonitis) 01/2004
1	Infections 09/2003

Drug/Important Bio-Agent (IBA)

6	Cytochromes b (Cytochrome b)IBA 07/2019 - 09/2003
5	Atovaquone (Mepron)FDA Link 01/2021 - 08/2003
5	Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA 01/2020 - 04/2005
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 11/2019
2	Pharmaceutical PreparationsIBA 07/2019 - 04/2005
1	Proguanil (Paludrine)FDA Link 01/2021
1	triokinaseIBA 01/2020
1	FMN cyclaseIBA 01/2020
1	GalactitolIBA 01/2020
1	Staphylococcal Protein A (Protein A)IBA 01/2020
1	FructoseIBA 01/2020
1	artemisinin (artemisinine)IBA 01/2020
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 11/2019
1	Mitochondrial DNA (mtDNA)IBA 07/2019
1	coenzyme Q10 (CoQ10)IBA 07/2019
1	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2016
1	Aconitate Hydratase (Aconitase)IBA 04/2016
1	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 12/2013
1	QuinolonesIBA 09/2012
1	ubiquinone 9IBA 05/2009
1	Nonsense Codon (Nonsense Mutation)IBA 05/2009
1	UbiquinoneIBA 05/2009
1	EnzymesIBA 04/2009
1	myxothiazolIBA 10/2005
1	stigmatellinIBA 10/2005
1	pyrachlostrobin (F 500)IBA 10/2005
1	azoxystrobinIBA 10/2005
1	lawsoneIBA 08/2003